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| Sleep,
Travel and Smoking |
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| Sleeping difficulties |
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Temporary sleeplessness can have a significant impact
on our health and general wellbeing. Sleep has a 'restorative'
effect on the human body and mind. It is not just a
matter of duration, the quality of sleep is also important.
Rapid eye movement (REM) sleep - this is the time we
dream - is essential and must be balanced. Lack of it
produces an unsatisfying sleep which leaves you feeling
tired. Excess alcohol can reduce the amount of REM sleep
and so should be avoided.
Sleeplessness can be caused by stress, problems or
jet lag. A number or bodily functions including body
temperature regulation, hormone secretion and sleep
operate rhythmically following an individual's 'body
clock'. The hormone, melatonin, secreted during the
hours of darkness, serves as the body's night-time indicator,
helping to regulate these rhythmic functions. The body-clock
rhythm, melatonin secretion, body temperature and sleep
are all interdependent. Any change in one factor will
upset the overall balance.; thus shift work and travel
across time zones de-synchronize the body clock, so
disrupting normal sleep.
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| Condition |
Insomnia |
| Symptoms |
Difficulty
in falling asleep; frequent awakenings; early awakenings |
| OTC Treatment |
- Sedatives
e.g. antihistamines such as diphenhydramine and
promethazine
NB: Antihistamines such as diphenhydramine should
be avoided by people with conditions such as asthma,
narrow angle glaucoma, prostatic hypertrophy (enlarged
prostate), bladder obstruction, pyloroduodenal obstruction
(blockage of the gut) or stenosing peptic ulcer
(stomach or duodenal ulcers). |
| Other self-help |
A number of simple self-help measures can help
you to manage your insomnia:
- Give yourself a relaxing bedtime routine (bath,
milky drink)
- Stop smoking – or at least cut down
- Find a way to reduce your stress levels e.g.
take a yoga class
- Avoiding daytime sleeping
- Avoiding exercise just before bedtime (but do
some regular exercise)
- Avoiding drinking tea, coffee and fizzy drinks
from early evening onwards
- Not working or watching television in bed
- Making sure your bed and bedroom is comfortable
- Not going to bed unless you feel tired.
Some herbal remedies are also regarded as useful
for insomnia due to their calming sedative effects
(see www.hsis.org).
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| Other information |
The causes
of temporary insomnia are:
- Stress/anxiety
- Illness e.g. depression, thyroid problems, menopausal
symptoms, night-time cough, pain
- Lifestyle e.g. shift work; jet-lag; over-tiredness;
in-take of stimulants, including caffeine, alcohol
and nicotine; exercising close to bedtime; daytime
sleeping; an uncomfortable, noisy or unfamiliar
environment. After travel across time zones, or
changes in working hours, it can take the body clock
a few days to two weeks to become resynchronised.
A number of OTC sleep-aid products i.e. those with
promethazine hydrochloride or diphenhydramine as
their active ingredient, are sedative antihistamines.
These OTC drugs are also:
- Available as tablets or liquid- Intended for short-term
use in the relief of temporary sleeplessness
- For adult use only (not for use in children under
16 years)
- Generally well tolerated
- Not to be taken with other sedatives, alcohol
or certain prescription drugs for depression
- Non-habit forming |
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| Travel (motion) sickness |
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Travel sickness affects many people of all ages, but
younger people seem to be more prone to its effects.
It affects many people of varying degrees when they
are subject to swaying or pitching movements. Sufferers
can experience motion sickness in cars, on planes and
on ships - especially when conditions are undulating
or rough!
The main organs of balance or equilibrium are located
in the inner ear. Each consists of three fluid-filled
canals, which contain tiny hairs. These respond to the
changes in the position of the head and transmit this
information to the brain where it is processed. Motion
sickness occurs when there is excessive stimulation
of the semi-circular canals; as a result the brain detects
major changes in the position of the head, yet sensory
input from the eyes seems out of step. This confusion
in sensations is thought to cause motion sickness.
The eyes and certain sensory cells in the skin and
internal tissues also help to maintain normal balance
by transmitting information to the brain on the body's
position relative to its external environment. Together,
sensory input from the semi-circular canals, eyes and
other sites control the body's balance.
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| Condition |
Travel
(Motion) Sickness |
| Symptoms |
Mild:
- Can be slight nausea
Severe:
- Vomiting
- Dizziness
- Sweating
- Unsteady gait
- Loss of balance
- Loss of co-ordination
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| OTC Treatment |
Two main groups of OTC drugs can be used to treat
motion sickness:
Anticholinergics: These are thought to
prevent motion sickness by controlling vomiting.
These drugs can cause dry mouth, blurred vision,
dizziness, constipation and urinary retention.
They are unsuitable for use in people who have
glaucoma, urinary problems, high blood pressure
or heart disease.
Antihistamines: Many antihistamines have
anti-nausea properties and proven effectiveness
in the treatment of motion sickness and the dizziness/nausea
associated with disorders of equilibrium.
Antihistamines available OTC for travel sickness
include promethazine, dimenhydrinate, meclozine
and cinnarizine.
These antihistamines can make you drowsy. Children
can take these drugs at half the adult dose or
less.
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| Other self-help |
The following measures can help reduce symptoms:
Road travel: ride in the centre of a moving
vehicle; look out of a window (especially children);
avoid reading and open the window for fresh air
Air travel: sit over the wings of an aeroplane.
Avoid alcohol.
Sea travel: ride in the centre of the vessel,
fixing the eyes on the horizon.
‘Travel bands’ are a non-drug option that can
be worn around the wrist and relieve pressure
by use of acupressure.
NB: Anyone prone to motion sickness should try
to take a remedy before leaving home as some are
ineffective once an attack has begun.
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| Smoking cessation |
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The immediate and long-term damaging effects of smoking
are generally well recognised. Some 14 million people
in the UK smoke; around 10 million of these would like
to stop and around 4 million are attempting to stop
at any given time.
Cigarettes are the most popular form of smoking in
the UK. Laboratory and clinical research has shown that
cigarettes contain about 4,000 chemicals, some of which
are highly toxic. Nicotine, a major constituent of tobacco
smoke, is highly addictive and largely responsible for
the pleasurable effects of smoking as it has mood enhancing
and anxiety relieving effects. It takes 7 seconds for
nicotine to reach the brain after inhalation.
Medically, nicotine is an addictive drug. Physical
dependence occurs because the body develops a tolerance
to nicotine, so that increasing amounts are needed to
produce the same 'pleasurable' effects. The smoker must
inhale more deeply or smoke more cigarettes to get he
desired effect. Psychological dependence on tobacco
occurs because smoking becomes a habit that is pleasurable
and sociable.
Smoking is viewed by the health profession as the most
preventable cause of death in the modern world. More
than 100,000 people die each year in the UK from smoking-related
diseases.
Many pharmacies offer non-judgemental support as part
of a smoking-cessation programme.
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| Condition |
Smoking
Cessation |
| Symptoms |
Symptoms
of nicotine withdrawal reach a peak in the first
1-2 days after stopping smoking but generally lessen
after 3-4 weeks. These symptoms include depression,
irritability, frustration, anger, anxiety, restlessness,
insomnia, difficulty concentrating, decreased heart
rate and an increased appetite. |
| OTC Treatment |
Nicotine Replacement Therapy: Several
OTC nicotine-replacement products are available
in the form of:
- Chewing gums
- Lozenges
- Sublingual tablets
- Transdermal patches
- Sprays and inhalers.
All these products treat nicotine dependence as
a step to help you stop smoking. When you use
these products properly you’ll gradually reduce
the dose of nicotine you have over several weeks,
help easing withdrawal symptoms and ultimately
breaking the physical nicotine dependence.
It is usual for a treatment course of 3 months
to be recommended and it’s important not to smoke
any cigarettes during this time.
Nicotine replacement is not recommended for pregnant
or breastfeeding women and should not be given
to children. Those with cardiovascular disease
should consult a GP.
Side effects of nicotine therapy include exacerbation
of the symptoms of peptic ulceration and gastritis.
Nicotine Transdermal patches: These are
small, self-adhesive patches that deliver nicotine
into the bloodstream through the skin, over the
course of several hours. Depending on the type
used, a fresh patch is applied daily for 16 or
24 hours over a period of 3 months.
The patches come in different strengths and nicotine
intake is reduced by progressively switching to
lower-strength patches over a treatment period.
Although the patches produce lower levels of nicotine
than a cigarette, blood levels are sufficient
to overcome cravings and withdrawal symptoms such
as restlessness and anxiety.
Local irritation can occur where the patch is
on the skin, so try to apply the patch to different
areas of skin.
Nicotine Gum: Nicotine is released from
the gum as it is chewed; it is absorbed through
the lining of the mouth. Nicotine gum should be
chewed correctly for maximum effectiveness and
fewer side effects. It should be chewed when there
is an urge to smoke. Once a strong taste is experienced,
the gum should be placed between the gum and cheek
until the taste has gone. The gum should be chewed
again until the taste subsides. This is repeated
over a 30-minute period.Nicotine gum is available
in 2mg and 4mg strengths. The stronger gum is
recommended for those who smoke more than 20 cigarettes
per day and are therefore more highly dependent
on nicotine.
Adverse effects associated with chewing gum include:
jaw pain; tooth trouble; throat irritation and
mouth ulcers.
Nicotine lozenges and sublingual tablets: Oral
nicotine replacement therapy is now also available
as a lozenge (containing 1mg of nicotine) and
sublingual tablet (containing 2mg nicotine).
Lozenges should be sucked every 1-2 hours when
you feel the urge to smoke, usually. 8-12 lozenges
per day. The recommended dose for sublingual tablets
is one tablet per hour (8-12 tablets per day)
for those smoking less than 20 cigarettes a day,
and 2 tablets per hour (16-24 tablets per day)
for those smoking more than 20 cigarettes a day.
Adverse effects include tooth trouble, throat
irritation and mouth ulcers.
Nicotine Inhaler: A nicotine inhaler comprises
a mouthpiece containing a replaceable cartridge
with 10mg of nicotine. This type of cessation
therapy helps to overcome the behavioural dependence
on cigarettes and, in particular, the habitual
hand-to-mouth activity. This product is therefore
most suitable for people who have a high behavioural
dependenceAnd who smoke less than 20 cigarettes
a day.
The nicotine from the inhalation device is absorbed
through the lining of the mouth. An inhaler produces
approximately one-third of the nicotine levels
achieved from cigarette smoking, which is adequate
to suppress withdrawal symptoms. The nicotine
vapour is inhaled by shallow puffing or deeply
inhaling, but the amount absorbed is similar whichever
technique is used.
To make sure enough nicotine is inhaled to depress
the withdrawal symptoms, 6-12 cartridges should
be used each day for the first 8 weeks. The number
of cartridges is then halved over the next two
weeks and then halved daily until none are used
by week 12.
Side effects diminish with use and include cough,
hiccups, sinusitis, irritation in the mouth and
a sore throat.
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| Other self-help |
There are several steps you can take to help
yourself control psychological dependence on –
and physical craving for – cigarettes:
Take one day at a time: Stopping smoking
is hard. Aim to get through the day.
Keep a positive attitude: Remain determined
and remind yourself why you want to stop smoking
Keep busy: Physical activity will take
your mind off the craving
Change Routine: Do something you don’t
normally do; something you won’t associate with
smoking.
Avoid temptation: Don’t allow yourself
to get into difficult situations where you might
be tempted to smoke; just one cigarette can upset
all your efforts
Eat the right food: If you feel more hungry
than usual try to eat more raw fruit and vegetables
and avoid snacking on high-calorie foods.
Ask for help if you need it: Visit your
pharmacy or GP – or use a help-line for extra
support. Join a support group, or talk to a friend
who has succeeded.
Get a buddy: Stopping along with someone
else can help provide motivation. Tell your friends
you have stopped as well as they will try to help
you.
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| Other information |
At low doses nicotine acts like a stimulant,
can ‘sharpen’ the senses and improve the ability
to concentrate. However, higher doses can cause
a calming and soothing effect. Habitual smokers
can readily adjust their nicotine dose to achieve
the desired effect: e.g. when anxious the smoker
will draw heavily o a cigarette to get the higher
dose needed to feel calmer.
In addition to its central affects on the brain,
nicotine has other effects on the body:
- Relaxation of the gut
- Relaxation of skeletal muscles, sometimes causing
tremor
- Increased secretion of certain hormones
- Increased heart rate and raised blood pressure
- Reduction in blood-flow, causing poor circulation.
Regular smokers become physically and psychologically
dependent on nicotine. Physical dependence arises
because the body develops a tolerance to nicotine
so that increasing amounts are needed to produce
the same pleasurable effects. The smoker must
inhale must inhale more deeply, or smoke more
cigarettes to get the desired effect. Psychological
dependence on tobacco occurs because smoking becomes
a habit and it becomes sociable and pleasurable.
Cigarette smoke: the ingredients Dangerous
ingredients – apart from nicotine – of cigarette
smoke include:
Carbon monoxide: prevents oxygen from binding
to red blood cells, damages blood cells
Hydrogen cyanide: affects respiration and
other body functions, damages blood vessels
Formaldehyde: irritant to membranes, is
carcinogenic
Hydrocarbons and nitrosamines: carcinogenic,
particularly in lung tissue
Amines: carcinogenic (casually associated
with bladder cancer in men)
- Heavy metals (arsenic, cadmium, lead, nickel)
are all poisons.
Health effects of smoking
- Increases risk of certain types of cancer (lung,
mouth, throat, oesophagus, stomach, bladder, kidney,
pancreas and cervix)
- The risk of dying from lung cancer is 22 times
higher for male smokers and 12 times higher for
female smokers – compared with non-smokers
- The risk of developing lung cancer increases
with the number of cigarettes smoked daily
- Smoking causes a 5-fold increase in the risk
of dying from lung problems such as chronic bronchitis
or emphysema
- Smoking causes a 2-4-fold increase in risk of
death from diseases of the heart and coronary
arteries; more smokers die from coronary heart
disease than from lung cancer.
- The risk of stroke is increased by about 50%
in 20-a-day smokers
- Smokers are more likely to get duodenal ulcers
– and these are more likely to take longer than
normal to heal
- Can cause premature and underweight babies to
be born to pregnant women who smoke. Can also
cause miscarriage and foetal malformation.
THE GOOD NEWS IS THAT STUDIES IN EX-SMOKERS
SHOW THAT THEIR RISK OF DYING FROM SMOKING-RELATED
DISEASE DECREASES WITH EACH YEAR OF ABSTINENCE:
- After 3 years of not smoking, the risk of having
a heart attack is reduced to that of a life-long
non-smoker
- After 10 cigarette-free years the risk of lung-cancer
is halved
- 15 years after stopping smoking, the risk of
developing almost any smoking-related disease
is reduced to little more than that of a life-long
non-smoker
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| Condition |
Loss
of appetite |
| Symptoms |
A lack
of feeling hungry. NOTE - If a person is losing
weight for no apparent reason then they should
seek medical advice. |
| OTC Treatment |
Vitamin and mineral supplements sold individually
or as tonics.
OTC tonics contain various combinations of the
following ingredients:
Caffeine: included to promote well-being;
it increases cardiovascular function, stimulates
the central nervous system, stimulates the action
of the heart and lungs, promotes urine formation
and can aid digestion.
Alcohol: Useful in small amounts to stimulate
gastric juices and stimulate appetite
Vitamins: A, B1 (thiamine),
B3 (niacin), D/D2
Minerals: including calcium/manganese/potassium/sodium
glycerophosphate, copper sulphate, ferric ammonium
citrate, manganese sulphate monohydrate, iron.
Some OTC tonics are not suitable for use in children,
while others can be recommended for children.
Tonics containing alcohol should not be used in
combination with other central nervous system
depressants. Caffeine-containing products should
not be used where caffeine-sensitivity is suspected.
Side effects of caffeine include nausea, headache
and insomnia.
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| Other information |
Illness or surgical operations can often leave
you feeling in need of a boost to help you recover
and gain strength.
It can be difficult to eat healthy, nutritious
food when you have little appetite. And even if
you do feel like eating, the recovery process
can be helped by supplementing the diet with additional
vitamins and minerals.
Vitamins and minerals are included in tonics because:
- Vitamins enhance the metabolism of proteins,
carbohydrates and fats; without these vitamins
the breakdown and assimilation of foods couldn’t
occur. Certain vitamins participate in the formation
of blood cells, hormones and nervous system chemicals.
- Minerals help the structural composition
of hard and soft body tissues; they also participate
in the action of enzyme systems, the contraction
of muscles, nerve reactions and blood clotting.
Most people will get enough vitamins if they eat
a health diet. See www.hsis.org
for more information on supplements and who can
benefit from taking them.
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| Stimulants
and Tonics |
| These are used as pick-me-ups or appetite promoters
in those who are ill or convalescing. They can help rebuild
strength and aid a speedy recovery. Stimulants contain
some similar ingredients to tonics but are more specifically
aimed at relieving fatigue and improving alertness. |
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| Condition |
Fatigue
and listlessness |
| Symptoms |
Feeling
more tired than usual; lacking energy |
| OTC Treatment |
Stimulants contain the following ingredients
in various combinations:
Caffeine: promotes well being; increases
cardiovascular function, stimulates the central
nervous system, stimulates the action of the heart
and lungs, promotes urine formation and can aid
digestion. This should not be used long term not
least because you can build up a dependence and
tolerance to caffeine.
Vitamins: B1 (thiamine), B2,
and B3 (niacin) enhance the metabolism
of proteins, carbohydrates and fats. Most people
will get enough vitamins if they eat a healthy
diet.
Glucose monohydrate: Boosts energy levels.
NB: Stimulants are not to be used by children.
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| Other information |
Any stimulant drug acts to excite the central
nervous system, increase alertness and lower fatigue.
Stimulants can be recommended to help overcome
feelings of tiredness resulting from illness,
overwork, stress or where you simply feel the
need for a boost of energy.
Caffeine, the most commonly used stimulant, is
present naturally in coffee, tea and some fizzy
drinks. Anyone taking an OTC stimulant shouldn’t
drink excess amounts of these as high doses of
caffeine can induce tremors and severe agitation.
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| MedicineChestOnline.com
is a directory of medicines and food supplements
that are available 'over the counter' (OTC) from
your pharmacist. The links below will take you to
pages detailing products which may help treat or
relieve the following symptoms: |
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NHS
Direct - The gateway to health information
on the internet.
Contains a list of information on health, including
features, healthy living, healthcare guide, conditions
and treatments and frequently asked questions. |
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